BDBM50008907 D-Saccharic Acid 1,4-Lactone

SMILES [H][C@@]1(OC(=O)[C@H](O)[C@H]1O)[C@H](O)C(O)=O

InChI Key InChIKey=XECPAIJNBXCOBO-UHFFFAOYSA-N

Data  1 KI  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50008907   

TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 5.67E+4nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using 4-methylumbelliferyl-beta-D-glucuronide hydrate as substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.85E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate incubated for 30 min prior to substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2020
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.83E+4nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2020
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2019
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by p-nitrophenyl-beta-D-glucuroni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate assessed as formation of p-nitrophenol incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate assessed as p-nitrophenol formation after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of beta-D-glucuronidase (unknown origin) assessed as reduction in p-nitrophenol formation using p-nitrophenyl-beta-D-glucuronide substarte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.84E+4nMAssay Description:β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed