BDBM50008825 1-Aminomethyl-3-cyclohexyl-6-methyl-isochroman-5-ol; hydrobromide::CHEMBL542436

SMILES Cc1ccc2[C@H](CN)O[C@@H](Cc2c1O)C1CCCCC1

InChI Key InChIKey=HSJYTPFWWPUYDT-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50008825   

Target5-hydroxytryptamine receptor 1A(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  54nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  58nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  86nMAssay Description:Binding affinity for dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1) dopamine receptor(Goldfish)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  100nMAssay Description:In vitro inhibition of dopamine stimulated adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  242nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  358nMAssay Description:Compound was tested in vitro for binding affinity for alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  1.87E+3nMAssay Description:In vitro binding affinity for dopamine uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Dog)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi:  1.92E+4nMAssay Description:Compound was tested in vitro for binding affinity for beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity for dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008825(CHEMBL542436 | 1-Aminomethyl-3-cyclohexyl-6-methyl...)
Affinity DataKi: >3.00E+4nMAssay Description:Compound was tested in vitro for binding affinity for alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed