BDBM50008824 1-Aminomethyl-6-bromo-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL543390

SMILES NC[C@@H]1O[C@@H](Cc2c(O)c(Br)ccc12)c1ccccc1

InChI Key InChIKey=SIPQEKQXLUBVAY-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50008824   

TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity for dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(1) dopamine receptor(Goldfish)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  32nMAssay Description:In vitro inhibition of dopamine stimulated adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  200nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  312nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  360nMAssay Description:Compound was tested in vitro for binding affinity for alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  569nMAssay Description:Binding affinity for dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  1.82E+3nMAssay Description:Compound was tested in vitro for binding affinity for alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  6.36E+3nMAssay Description:Compound was tested in vitro for binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Dog)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi:  1.84E+4nMAssay Description:Compound was tested in vitro for binding affinity for beta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008824(CHEMBL543390 | 1-Aminomethyl-6-bromo-3-phenyl-isoc...)
Affinity DataKi: >3.00E+4nMAssay Description:In vitro binding affinity for dopamine uptake siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed