BDBM50008784 CHEMBL288704::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(2-fluoro-ethyl)-2,3-dimethoxy-benzamide

SMILES CCN1CCC[C@H]1CNC(=O)c1cc(CCF)cc(OC)c1OC

InChI Key InChIKey=ARAWZUUSXRTRLM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008784   

TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008784(CHEMBL288704 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50008784(CHEMBL288704 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed