BDBM50008733 1-(4-Cyanobenzyl)-1H-imidazole::4-((1H-imidazol-1-yl)methyl)benzonitrile::4-Imidazol-1-ylmethyl-benzonitrile::CHEMBL349822

SMILES N#Cc1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=LUSFCTSUDCCYLQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50008733   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of rat microsomal 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 368nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 372nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 7nMAssay Description:Inhibition of aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate after 30 mins by fluorescence-based colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed