BDBM50008521 CHEMBL4061620

SMILES Cc1ccc(cc1)C(=O)NCC1N(CCCl)CCc2ccccc12

InChI Key InChIKey=MYZICIOFVNMBGU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008521   

TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008521(CHEMBL4061620)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells co-expressing Galpha 15 assessed as increase in intracellular calcium release incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008521(CHEMBL4061620)
Affinity DataIC50: 200nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50008521(CHEMBL4061620)
Affinity DataIC50: 2.94E+3nMAssay Description:Agonist activity at human KOR expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase-mediated cAMP accumulation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details Article
PubMed