BDBM50008520 2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentahydroxy-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-3-(2-methyl-propane-2-sulfonyl)-propionamide::CHEMBL357253

SMILES CC(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=SEGJVTDZQVOHPV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50008520   

TargetRenin(Rat)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for 50% inhibition of rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 110nMAssay Description:Concentration required for 50% inhibition of dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPepsin A-5(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration required for 50% inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 11nMAssay Description:Concentration required for 50% inhibition of rhesus monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 4.40nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 4.5nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(CHEMBL357253 | 2-Benzyl-N-[1-(1-cyclohexylmethyl-2...)
Affinity DataIC50: 100nMAssay Description:Concentration required for 50% inhibition of sheep plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed