BDBM50008222 CHEMBL3235118

SMILES CC(C)c1cc(c(O)cc1O)-n1nnc(C(=O)NCCCCCCC(=O)NO)c1-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=IBHAGSBJXPUIFA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50008222   

TargetHistone deacetylase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human HDAC-1 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human HDAC-2 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human HDAC-3/NCOR2 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 7.15E+4nMAssay Description:Inhibition of human HDAC-4 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human HDAC-5 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human HDAC-7 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 717nMAssay Description:Inhibition of human HDAC-8 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human HDAC-11 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50008222(CHEMBL3235118)
Affinity DataIC50: 31nMAssay Description:Displacement of GM-FITC from full-length recombinant human Hsp90-alpha after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed