BDBM50008157 4-(1-{1-[1-Cyclohexylmethyl-3,3-difluoro-2-hydroxy-3-(2-methyl-butylcarbamoyl)-propylcarbamoyl]-but-3-enylcarbamoyl}-2-phenyl-ethylsulfamoyl)-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL32239

SMILES CC[C@H](C)CNC(=O)C(F)(F)C(O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCN(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=XEJQSPNBNGMTCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008157   

TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008157(CHEMBL32239 | 4-(1-{1-[1-Cyclohexylmethyl-3,3-difl...)
Affinity DataIC50: 259nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008157(CHEMBL32239 | 4-(1-{1-[1-Cyclohexylmethyl-3,3-difl...)
Affinity DataIC50: 1.5nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed