BDBM50008146 2-[3-(4-Methoxy-phenyl)-2-(morpholine-4-sulfonylamino)-propionylamino]-pent-4-enoic acid [1-cyclohexylmethyl-3,3-difluoro-2-hydroxy-3-(2-morpholin-4-yl-ethylcarbamoyl)-propyl]-amide; Hydrate::CHEMBL280543

SMILES COc1ccc(C[C@H](NS(=O)(=O)N2CCOCC2)C(=O)N[C@@H](CC=C)C(=O)N[C@@H](CC2CCCCC2)C(O)C(F)(F)C(=O)NCCN2CCOCC2)cc1

InChI Key InChIKey=VMKHTPDJHSKOJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008146   

TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008146(CHEMBL280543 | 2-[3-(4-Methoxy-phenyl)-2-(morpholi...)
Affinity DataIC50: 1.5nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008146(CHEMBL280543 | 2-[3-(4-Methoxy-phenyl)-2-(morpholi...)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed