BDBM50008126 5-Cyclohexyl-2,2-difluoro-3-hydroxy-4-{3-(1H-imidazol-4-yl)-2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-propionylamino}-pentanoic acid (2-morpholin-4-yl-ethyl)-amide; methyl alcohol::CHEMBL28311

SMILES OC([C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(F)(F)C(=O)NCCN1CCOCC1

InChI Key InChIKey=BVPCJACDNLTJEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008126   

TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008126(CHEMBL28311 | 5-Cyclohexyl-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: 3nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008126(CHEMBL28311 | 5-Cyclohexyl-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed