BDBM50008039 3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid::CHEMBL284394

SMILES CN1[C@@H]2CCC1C([C@H](C2)OC(=O)c1ccccc1)C(O)=O

InChI Key InChIKey=GVGYEFKIHJTNQZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50008039   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 3.98E+6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to Dopamine transporter in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 3.92E+5nMAssay Description:Inhibition of [3H]mazindol binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50008039(CHEMBL284394 | 3-Benzoyloxy-8-methyl-8-aza-bicyclo...)
Affinity DataIC50: 1.95E+5nMAssay Description:Potency for the inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed