BDBM50007899 CHEMBL3234318

SMILES CCc1nc(N)nc(N)c1C#CC(C)c1ccc(cc1OC)-c1ccc(cc1)C(=O)OC

InChI Key InChIKey=NAQVHWHJQHENSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007899   

TargetDihydrofolate reductase(Yeast)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50007899(CHEMBL3234318)
Affinity DataIC50: 46nMAssay Description:Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50007899(CHEMBL3234318)
Affinity DataIC50: 49nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed