BDBM50007848 8-Cyclopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL53737

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC1

InChI Key InChIKey=MQNGKZXCIMDJDW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007848   

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50007848(CHEMBL53737 | 8-Cyclopropyl-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  1.5nMAssay Description:Binding ability of adenosine A1 receptor by using [3H]CHA as radioligand in rat whole brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50007848(CHEMBL53737 | 8-Cyclopropyl-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  42nMAssay Description:Antagonist activity against adenosine A1 receptor in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50007848(CHEMBL53737 | 8-Cyclopropyl-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  42nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50007848(CHEMBL53737 | 8-Cyclopropyl-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  240nMAssay Description:Antagonistic activity against adenosine A2 receptor in rat adipocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50007848(CHEMBL53737 | 8-Cyclopropyl-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  706nMAssay Description:Displacement of [3H]-CGS- from Adenosine A2a receptor of rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article