BDBM50007620 CHEMBL3233084

SMILES O=C(COc1ccccc1C#N)NCCc1nc2ccccc2[nH]1

InChI Key InChIKey=HMWNGSGLJVRMTB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007620   

TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50007620(CHEMBL3233084)
Affinity DataIC50: 6.51E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine expressed in Escherichia coli SG13009 using Z-FR-AMC as substrate after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50007620(CHEMBL3233084)
Affinity DataIC50: 6.51E+4nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCathepsin S(Human)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50007620(CHEMBL3233084)
Affinity DataKi:  220nMAssay Description:Binding affinity to Cathepsin S (unknown origin) assessed as inhibition constant measured after 22 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed