BDBM50007506 8-{3-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL418526

SMILES Cc1cccc(N2CCN(CCCON3C(=O)CC4(CCCC4)CC3=O)CC2)c1C

InChI Key InChIKey=OVGOHHDHXOMVSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007506   

TargetD(2) dopamine receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007506(CHEMBL418526 | 8-{3-[4-(2,3-Dimethyl-phenyl)-piper...)
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007506(CHEMBL418526 | 8-{3-[4-(2,3-Dimethyl-phenyl)-piper...)
Affinity DataIC50: 170nMAssay Description:Compound was measured for affinity at 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007506(CHEMBL418526 | 8-{3-[4-(2,3-Dimethyl-phenyl)-piper...)
Affinity DataIC50: 250nMAssay Description:Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed