BDBM50007485 8-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl)::CHEMBL10880

SMILES Clc1ccccc1N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key InChIKey=RZUNPHILLASKHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007485   

Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007485(CHEMBL10880 | 8-{3-[4-(2-Chloro-phenyl)-piperazin-...)
Affinity DataIC50: 220nMAssay Description:Compound was measured for affinity at 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007485(CHEMBL10880 | 8-{3-[4-(2-Chloro-phenyl)-piperazin-...)
Affinity DataIC50: 680nMAssay Description:Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed