BDBM50007462 1-[4-(8-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone::CHEMBL344942

SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(F)cc2-[#6]-[#6]-c2cccnc-12

InChI Key InChIKey=DJQKUCOLEUHFHY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007462   

TargetPlatelet-activating factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007462(CHEMBL344942 | 1-[4-(8-Fluoro-5,6-dihydro-benzo[5,...)
Affinity DataIC50: 670nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007462(CHEMBL344942 | 1-[4-(8-Fluoro-5,6-dihydro-benzo[5,...)
Affinity DataKi:  720nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed