BDBM50007412 1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine::CHEMBL325262

SMILES Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1

InChI Key InChIKey=LJDXYTBGUJEQSY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007412   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  19nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  128nMAssay Description:Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  488nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi:  498nMAssay Description:Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50007412(CHEMBL325262 | 1-(3-Chloro-phenyl)-4-(3-phenyl-pro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed