BDBM50007377 2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL320882

SMILES CN(C(CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=AEJOEPSMZCEYJN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007377   

TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007377(CHEMBL320882 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50007377(CHEMBL320882 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity for human Kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50007377(CHEMBL320882 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  24nMAssay Description:Binding affinity for human Delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50007377(CHEMBL320882 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataKi:  53nMAssay Description:Binding affinity for human Mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed