BDBM50007284 CHEMBL101600::Sodium; 6-{2-[cyclohexyl-(2,2-dimethyl-butyrylamino)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate

SMILES CCC(C)(C)C(=O)NC(C1CCCCC1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=XAFSODPXPFYGDP-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007284   

LigandPNGBDBM50007284(CHEMBL101600 | Sodium; 6-{2-[cyclohexyl-(2,2-dimet...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50007284(CHEMBL101600 | Sodium; 6-{2-[cyclohexyl-(2,2-dimet...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50007284(CHEMBL101600 | Sodium; 6-{2-[cyclohexyl-(2,2-dimet...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50007284(CHEMBL101600 | Sodium; 6-{2-[cyclohexyl-(2,2-dimet...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed