BDBM50007272 CHEMBL102168::Sodium; 6-[4'-fluoro-5-(4-fluoro-phenylsulfanyl)-3-isopropyl-biphenyl-2-yloxy]-3,5-dihydroxy-hexanoate

SMILES CC(C)c1cc(Sc2ccc(F)cc2)cc(-c2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=UFSXOKMGOHBXIH-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007272   

LigandPNGBDBM50007272(CHEMBL102168 | Sodium; 6-[4'-fluoro-5-(4-fluoro-ph...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50007272(CHEMBL102168 | Sodium; 6-[4'-fluoro-5-(4-fluoro-ph...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed