BDBM50007247 1,7,8-Trimethyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL317604

SMILES Cc1ccc2nc3[nH]c(=O)n(C)c3cc2c1C

InChI Key InChIKey=PJRUEHQERHHYKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007247   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007247(CHEMBL317604 | 1,7,8-Trimethyl-1,3-dihydro-imidazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP hydrolysis by human platelet phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007247(CHEMBL317604 | 1,7,8-Trimethyl-1,3-dihydro-imidazo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of hydrolysis of c-AMP phosphodiesterase in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed