BDBM50007197 CHEMBL3237869

SMILES [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NCCC(COCc1ccccc1)COCc1ccccc1)NC(=O)c1ccccc1

InChI Key InChIKey=VMNWBKJOXQEROK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007197   

TargetProteasome subunit beta type-7(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007197(CHEMBL3237869)
Affinity DataIC50: 130nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome using Ac-nLPnLD-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProteasome subunit beta type-7(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007197(CHEMBL3237869)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Ac-RLR-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProteasome subunit beta type-7(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007197(CHEMBL3237869)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed