BDBM50007152 1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-diol::CHEMBL313304

SMILES NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccc(I)cc1

InChI Key InChIKey=IFTXVACPDRUAPN-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007152   

TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007152(CHEMBL313304 | 1-Aminomethyl-3-(4-iodo-phenyl)-iso...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007152(CHEMBL313304 | 1-Aminomethyl-3-(4-iodo-phenyl)-iso...)
Affinity DataEC50:  2nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007152(CHEMBL313304 | 1-Aminomethyl-3-(4-iodo-phenyl)-iso...)
Affinity DataKi:  14nMAssay Description:Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007152(CHEMBL313304 | 1-Aminomethyl-3-(4-iodo-phenyl)-iso...)
Affinity DataKi:  1.06E+3nMAssay Description:Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed