BDBM50007141 1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol::CHEMBL87172

SMILES NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=ILWGLMLPVXFDGW-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007141   

TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007141(CHEMBL87172 | 1-Aminomethyl-3-benzhydryl-isochroma...)
Affinity DataEC50:  100nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007141(CHEMBL87172 | 1-Aminomethyl-3-benzhydryl-isochroma...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007141(CHEMBL87172 | 1-Aminomethyl-3-benzhydryl-isochroma...)
Affinity DataKi:  530nMAssay Description:Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007141(CHEMBL87172 | 1-Aminomethyl-3-benzhydryl-isochroma...)
Affinity DataKi:  2.61E+3nMAssay Description:Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed