BDBM50007077 4-(2-methoxy-4-(2-nitrovinyl)phenoxysulfonyl)benzoic acid::4-[2-Methoxy-4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid::CHEMBL418907

SMILES COc1cc(\C=C\[N+]([O-])=O)ccc1O[S+]([O-])(=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=AQOKHTQLSPHEKY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007077   

TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
TBA

Curated by ChEMBL
LigandPNGBDBM50007077(CHEMBL418907 | 4-[2-Methoxy-4-(2-nitro-vinyl)-phen...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Abelson murine leukemia virus p60 v-ablMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007077(CHEMBL418907 | 4-[2-Methoxy-4-(2-nitro-vinyl)-phen...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007077(CHEMBL418907 | 4-[2-Methoxy-4-(2-nitro-vinyl)-phen...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of the epidermal growth factor receptor expressed in A431 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007077(CHEMBL418907 | 4-[2-Methoxy-4-(2-nitro-vinyl)-phen...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed