BDBM50006853 CHEMBL315211::N-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonamic acid methyl ester

SMILES COC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C

InChI Key InChIKey=IEWAGORIVPFRDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006853   

TargetRenin(Human)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006853(CHEMBL315211 | N-(1-Cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50: 0.280nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006853(CHEMBL315211 | N-(1-Cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for the percent inhibition of Cathepsin D in BovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed