BDBM50006677 1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl]-benzene::1,2,3-Trimethoxy-5-[2-(4-methoxy-phenyl)-vinyl]-benzene::10Z-3,4,4',5-tetramethoxystilbene::3,4,4',5-tetramethoxy-(Z)-stilbene::5-(4-methoxystyryl)-1,2,3-trimethoxybenzene::CHEMBL47426::Trans-1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)-vinyl]-benzene (13)

SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1

InChI Key InChIKey=GGFQQRXTLIJXNY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006677   

TargetTyrosinase(Mouse)
Indian Institute of Integrative Medicine

LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Concentration required to inhibit polymerization of tubulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
University of Salford

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 200nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2019
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: 1.30E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed