BDBM50006476 CHEMBL305064::[6-(5,7-Difluoro-benzothiazol-2-ylmethyl)-5-oxo-5,6-dihydro-pyrido[2,3-d]pyridazin-8-yl]-acetic acid

SMILES OC(=O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c2cccnc12

InChI Key InChIKey=KLGRUNSKORTTKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006476   

TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006476(CHEMBL305064 | [6-(5,7-Difluoro-benzothiazol-2-ylm...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed