BDBM50006426 CHEMBL302255::{1-[1-[1-Cyclohexylmethyl-2-hydroxy-3-(5-phenylamino-[1,3,4]thiadiazol-2-ylsulfanyl)-propylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CSc1nnc(Nc2ccccc2)s1

InChI Key InChIKey=LQSQUHQXOXSJLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006426   

TargetRenin(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006426(CHEMBL302255 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50: 3.31E+3nMAssay Description:The compound was tested in vitro for inhibition of human plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed