BDBM50006413 CHEMBL65037::Sodium; 7-[5-(4-fluoro-phenyl)-3-isopropyl-1-pyridin-2-yl-1H-pyrazol-4-yl]-3,5-dihydroxy-heptanoate

SMILES CC(C)c1nn(c(c1CCC(O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccn1

InChI Key InChIKey=ZRSDASSNOLAFQV-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006413   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006413(CHEMBL65037 | Sodium; 7-[5-(4-fluoro-phenyl)-3-iso...)
Affinity DataIC50: 110nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed