BDBM50006411 CHEMBL2367470::Sodium; 7-[5-(4-fluoro-phenyl)-1-pyridin-2-yl-3-trifluoromethyl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate

SMILES O=C([O-])C[C@H](O)C[C@H](O)/C=C/c2c(C(F)(F)F)nn(c1ccccn1)c2c3ccc(F)cc3

InChI Key InChIKey=GNVFSPKLVLISEJ-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006411   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006411(CHEMBL2367470 | Sodium; 7-[5-(4-fluoro-phenyl)-1-p...)
Affinity DataIC50: 17nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed