BDBM50006409 CHEMBL2367478::Sodium; 7-[5-(4-fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate

SMILES CC(C)c3nn(c1ccccc1)c(c2ccc(F)cc2)c3/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-]

InChI Key InChIKey=FJBDYSRTNGPUEY-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006409   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006409(CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)
Affinity DataIC50: 7.20nMAssay Description:Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006409(CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)
Affinity DataIC50: 7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed