BDBM50006179 (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethylamino]-hexanoylamino}-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid (3-imidazol-1-yl-propyl)-amide::5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethylamino]-hexanoylamino}-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid (3-imidazol-1-yl-propyl)-amide::CHEMBL49172

SMILES CCCC[C@H](N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)OCOC)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)C[C@@H](C(C)C)C(=O)NCCCn1ccnc1

InChI Key InChIKey=YVBYQUBEKLSQSW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006179   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 2nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 330nMAssay Description:Tested in vitro for its ability to inhibit the ferret plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 7.60nMAssay Description:Tested in vitro for its ability to inhibit the human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 24nMAssay Description:Tested in vitro for its ability to inhibit the dog plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 7.30E+3nMAssay Description:Tested in vitro for its ability to inhibit the rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179(CHEMBL49172 | (2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-...)
Affinity DataIC50: 7.60nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed