BDBM50006132 CHEMBL297929::[1-[1-(1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-3-methyl-butylcarbamoyl]-2-(4-iodo-phenyl)-ethyl]-carbamic acid ethyl ester

SMILES CCOC(=O)N[C@@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C

InChI Key InChIKey=TYLAYGSYBANABY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006132   

TargetRenin(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50006132(CHEMBL297929 | [1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50: 2.40nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50006132(CHEMBL297929 | [1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory activity against renin at 10e-6 (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50006132(CHEMBL297929 | [1-[1-(1-Cyclohexylmethyl-2,3-dihyd...)
Affinity DataIC50: 300nMpH: 7.4Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed