BDBM50006123 2,3-Diphenyl-cyclopropanecarboxylic acid [1-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-thiazol-4-yl-ethyl]-amide::CHEMBL296051

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)C1[C@@H]([C@@H]1c1ccccc1)c1ccccc1

InChI Key InChIKey=BUPQQGHDPSNMRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006123   

TargetRenin(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50006123(CHEMBL296051 | 2,3-Diphenyl-cyclopropanecarboxylic...)
Affinity DataIC50: 1.10nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50006123(CHEMBL296051 | 2,3-Diphenyl-cyclopropanecarboxylic...)
Affinity DataIC50: 810nMpH: 7.4Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed