BDBM50005823 CHEMBL291033::[2-(1H-Indol-3-yl)-1-methyl-1-phenethylcarbamoyl-ethyl]-carbamic acid adamantan-2-yl ester

SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)NCCc1ccccc1

InChI Key

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50005823   

TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 48nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex Cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 48nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 377nMAssay Description:Inhibition of binding of [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 640nMAssay Description:Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 380nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to rat pancreas cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Mouse)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 330nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Parke-Davis Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataIC50: 620nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to rat pancreas cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataKi:  87nMAssay Description:Tested for inhibition of [3H]pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50005823(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Affinity DataKi:  1.89E+3nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type A receptor in guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed