BDBM50005783 CHEMBL3235851

SMILES COc1ccc(OC)c(c1)C(=O)N1CCc2nc(ncc2C1)N1CCN(CC1)c1ncccn1

InChI Key InChIKey=RUIVLHSVDWMXGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005783   

TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005783(CHEMBL3235851)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of full-length HSP90 (unknown origin) expressed in Escherichia coli assessed as inhibition of ATPase activity after 3 hrs by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005783(CHEMBL3235851)
Affinity DataIC50: 4.04E+4nMAssay Description:Displacement of FITC-geldanamycin from HSP90 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed