BDBM50005744 CHEMBL3235463

SMILES ONC(=O)\C=C\c1ccc(cc1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50005744   

TargetHistone deacetylase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 6.96E+3nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human HDAC4 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50005744(CHEMBL3235463)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed