BDBM50005681 2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylamino-propyl ester::CHEMBL286008

SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1

InChI Key InChIKey=HPHMHCRNJVKYKE-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50005681   

TargetPancreatic alpha-amylase(Rat)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataIC50: 10nMAssay Description:Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.5nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M4 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.70nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M3 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  1.90nMAssay Description:Antimuscarinic potency and subset specificity was characterised by inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M1 subtypeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50005681(CHEMBL286008 | 2-Cyclohexyl-2-phenyl-propionic aci...)
Affinity DataKi:  27nMAssay Description:Antimuscarinic potency and subset specificity was characterised by its inhibition of the [3H]NMS Binding to Muscarinic acetylcholine receptor M2 subt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed