BDBM50005560 3-Benzoyloxy-8-methyl-8-azonia-bicyclo[3.2.1]octane::Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester (tropine benzoate)::PSEUDOCOCAINE::R-Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester

SMILES COC(=O)[C@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2

InChI Key

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50005560   

TargetSodium-dependent dopamine transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005560(Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl...)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005560(Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl...)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005560(Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl...)
Affinity DataKi:  1.04E+4nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005560(Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed