BDBM50005544 8-Methyl-3-(4-nitro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL177595

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(cc1)[N+]([O-])=O)N2C

InChI Key InChIKey=JWBRJGZNZCKAEB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50005544   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 213nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 10nMAssay Description:Affinity against cocaine binding site of dopamine transporter in rat striatum using [3H]2b as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 137nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 903nMAssay Description:Inhibition of dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005544(CHEMBL177595 | 8-Methyl-3-(4-nitro-phenyl)-8-aza-b...)
Affinity DataIC50: 616nMAssay Description:Inhibition of dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed