BDBM50005376 8-Indan-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-Indan-2-yl-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CHEMBL132441

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1Cc2ccccc2C1

InChI Key InChIKey=HTZOCGVMYAKXOF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005376   

TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50005376(8-Indan-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  64.3nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50005376(8-Indan-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  220nMAssay Description:Binding affinity against adenosine A1 receptor using N6-[3H]cyclohexyladenosine as radioligand in guinea pig forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50005376(8-Indan-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity against adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed