BDBM50005034 7-Chloro-5-iodo-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid::CHEMBL22895

SMILES OC(=O)c1cc(O)c2c(I)cc(Cl)cc2n1

InChI Key InChIKey=YXXRRQFCBIAGLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005034   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005034(CHEMBL22895 | 7-Chloro-5-iodo-4-oxo-1,4-dihydro-qu...)
Affinity DataIC50: 14nMAssay Description:Inhibition of the binding of [3H]L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005034(CHEMBL22895 | 7-Chloro-5-iodo-4-oxo-1,4-dihydro-qu...)
Affinity DataIC50: 32nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed