BDBM50004920 CHEMBL284746::S(-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol

SMILES Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O

InChI Key InChIKey=JUDKOGFHZYMDMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004920   

TargetD(1A) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50004920(CHEMBL284746 | S(-)SKF 383931-Phenyl-2,3,4,5-tetra...)
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50004920(CHEMBL284746 | S(-)SKF 383931-Phenyl-2,3,4,5-tetra...)
Affinity DataIC50: 1.97E+5nMAssay Description:Tested for Dopamine receptor activity by the inhibition against spiroperidol binding to rat caudate tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50004920(CHEMBL284746 | S(-)SKF 383931-Phenyl-2,3,4,5-tetra...)
Affinity DataIC50: 7.20E+5nMAssay Description:Displacement of [3H]YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed