BDBM50004777 CHEMBL3233742

SMILES COc1cc2ccccc2c(Cc2c([nH][nH]c2=O)-c2ccc(C)cc2)c1O

InChI Key InChIKey=KAEMGFMCDSXJIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004777   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004777(CHEMBL3233742)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004777(CHEMBL3233742)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT2 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004777(CHEMBL3233742)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SIRT3 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed