BDBM50004764 CHEMBL3233733

SMILES Cc1ccc(cc1)-c1[nH][nH]c(=O)c1Cc1c(O)ccc2cc(ccc12)-c1ccccc1

InChI Key InChIKey=QTHNHFXMMJFBBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50004764   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004764(CHEMBL3233733)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004764(CHEMBL3233733)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of SIRT2 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Fred Hutchinson Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50004764(CHEMBL3233733)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of SIRT3 (unknown origin) by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed