BDBM50004664 CHEMBL107892::N-[2-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethyl]-4,6-dinitro-benzene-1,3-diamine

SMILES CN(C)Cc1ccc(CSCCNc2cc(N)c(cc2[N+]([O-])=O)[N+]([O-])=O)o1

InChI Key InChIKey=HAFSYIUXFNUVMN-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50004664   

TargetMuscarinic acetylcholine receptor M1(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of [3H]pirenzepine binding to mouse muscarinic acetylcholine receptor M1 from cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibition of human butryl cholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50: 6.80E+3nMAssay Description:Binding affinity against mouse Muscarinic acetylcholine receptor M2 using heart tissue and [3H]N-methylscopolamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataKi:  460nMAssay Description:Ability to displace [3H]oxotremorine ([3H]-OXO-M) from mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004664(CHEMBL107892 | N-[2-(5-Dimethylaminomethyl-furan-2...)
Affinity DataKi:  9.50E+3nMAssay Description:Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed