BDBM50004475 CCK7 analogue::CHEMBL439591::N-(1-Carbamoyl-2-phenyl-ethyl)-3-{2-[3-(1H-indol-3-yl)-2-(2-{2-[3-(4-sulfonyl-oxy-phenyl)-propionylamino]-hexanoylamino}-acetylamino)-propionylamino]-4-methyl-pentanoylamino}-succinamic acid

SMILES CCCC[C@H](NC(=O)CCc1ccc(OS(O)(=O)=O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=ZYFZAOVAALGAJO-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50004475   

LigandPNGBDBM50004475(CCK7 analogue | CHEMBL439591 | N-(1-Carbamoyl-2-ph...)
Affinity DataEC50:  3.70nMAssay Description:Evaluated in vitro for maximal stimulatory activity for amylase release relative to CCK-8 in guinea pig tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004475(CCK7 analogue | CHEMBL439591 | N-(1-Carbamoyl-2-ph...)
Affinity DataIC50: 1.40nMAssay Description:Evaluated in vitro for its binding affinity towards cholecystokinin type B receptor of guinea pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004475(CCK7 analogue | CHEMBL439591 | N-(1-Carbamoyl-2-ph...)
Affinity DataIC50: 4.70nMAssay Description:Evaluated in vitro for its binding affinity towards cholecystokinin type A receptor of guinea pig pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004475(CCK7 analogue | CHEMBL439591 | N-(1-Carbamoyl-2-ph...)
Affinity DataIC50: 4.70nMAssay Description:In vitro ability to inhibit [125I]Bolton-Hunter-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed